Join 100,000+ other patients

Compounded · GLP-1 Care for Women 40+

Tirzepatide Injection

Join 100,000+ other patients

For weight gain that
feels different after 40.

See if you qualify

No charge today Takes about 3 minutes

Board-certified physicians
State-licensed pharmacies
Same-day prescriptions
2-day shipping

Compounded tirzepatide injection — Cypress Health

2-day shipping · direct-to-door
Cancel anytime on monthly · save more on 6 or 12-month plans
Includes clinician oversight, dose escalation, and side-effect support

Your care

U.S.-LicensedPhysicians

State-LicensedCompounding Pharmacies

HIPAACompliant

Available inAll 50 US states

Pricing

Choose your plan.

Save more with the 6 or 12-month plan.

Why tirzepatide

Two receptors. One injection. A different conversation.

Compounded tirzepatide injection for weight loss

Semaglutide acts on the GLP-1 receptor — one of two pathways involved in regulating appetite, satiety, and metabolism. Tirzepatide acts on both GLP-1 and GIP. The dual mechanism is delivered with the same once-weekly cadence.

For some women in midlife, the dual mechanism may be a fit when other approaches haven't been a match. Whether that's true for you isn't something we can promise — only your clinician can determine appropriateness, based on your medical history, current medications, and goals.

The intake is the first step. Outcomes vary; tirzepatide is not appropriate for everyone.

Dosing

A measured start. Adjusted as you go.

Weeks 1–4 · Starting dose

2.5 mg once weekly. Most patients tolerate this well; mild GI symptoms are common in the first week or two and typically settle.

Weeks 5+ · Dose escalation

Your clinician adjusts your dose based on response and tolerance — typically 5 mg, 7.5 mg, 10 mg, with options up to 15 mg as appropriate.

Ongoing · Care, not just refills

Your plan includes ongoing clinician oversight, dose adjustment, side-effect support, and lab review when needed. We don't disappear after the first ship.

Side effects & safety

What to know before you start.

Woman in midlife smiling, considering her tirzepatide care plan

Most common: nausea, decreased appetite, mild diarrhea, constipation, fatigue. These are typically dose-related and most pronounced in the first week of each new dose.

Less common but important: pancreatitis, gallbladder issues, low blood sugar (especially if you also take insulin or sulfonylureas). Tell your clinician about all current medications.

Muscle mass during treatment: GLP-1 therapy can be associated with loss of lean mass, particularly in women in midlife. Your clinician will discuss strategies to protect muscle — typically resistance training and adequate dietary protein — as part of your care plan.

Not appropriate if: you have a personal or family history of medullary thyroid carcinoma or MEN2; you're pregnant, planning pregnancy, or breastfeeding; or you have severe GI disease or end-stage organ disease.

Questions

Answers to
common questions.

How is compounded tirzepatide prepared?

Compounded by a licensed 503A pharmacy on a per-patient basis.

Compounded tirzepatide is prepared by a state-licensed U.S. pharmacy operating under Section 503A of the Federal Food, Drug, and Cosmetic Act. Each preparation is dispensed per-patient based on a licensed clinician's prescription. Compounded preparations are not interchangeable with branded medications and may differ in formulation, strength, and clinical profile. Your clinician will help determine whether compounded tirzepatide is appropriate for your specific health profile.

How does tirzepatide compare to semaglutide?

Dual GLP-1/GIP mechanism — greater average weight loss in published trials.

Tirzepatide acts on two appetite-regulating hormone pathways — GLP-1 and GIP — while semaglutide acts on GLP-1 alone. The dual mechanism translated to greater average weight loss in published trials. SURMOUNT-1 (Jastreboff et al., NEJM 2022) showed up to ~20.9% body weight loss at the 15 mg weekly dose over 72 weeks. For women who've plateaued on semaglutide or who are starting GLP-1 therapy later in life, tirzepatide is often considered. Outcomes from branded clinical trials cannot be directly attributed to compounded preparations.

When am I charged?

Not until a clinician confirms your eligibility — typically within 24–48 hours.

You're not charged when you submit. Your card is securely saved while a licensed clinician reviews your assessment, typically within 24 to 48 hours. If approved, you'll receive an email confirmation before any charge. If not approved, you're not charged.

Will I need to stay on treatment after I reach my goal?

Most people regain weight without a structured maintenance plan. We plan that step with you.

The available evidence shows most people regain weight when GLP-1 or GLP-1/GIP therapy stops without a structured maintenance plan; the SURMOUNT-4 withdrawal trial (Aronne et al., JAMA 2024) showed weight regain after tirzepatide was discontinued. Options include stepping down to a lower maintenance dose, weaning off with structured resistance training and protein-forward eating to protect lean mass, or continuing at full dose. The right path is decided with you when the time comes — not around you.

Can I cancel?

Cancel anytime on monthly.

The 1-month plan can be cancelled at any time. The 6 and 12-month plans are billed upfront for the full term and shipped quarterly — you can choose not to renew at the end of your term.

Is insurance required?

No — transparent flat-rate pricing, no hidden fees.

No. Cypress offers transparent, flat-rate pricing without insurance and no hidden fees. Medication, supplies, and shipping are all included.

Can I use my FSA/HSA?

Yes — itemized receipts provided for self-submission.

Yes. HSA and FSA cards are accepted on any plan. We also provide itemized receipts in case you need to self-submit to your benefits provider.

See if tirzepatide is right for you.

The 3-minute medical screener is free. If you're a candidate, your clinician typically follows up within 24 hours.