Join 100,000+ other patients

Compounded · GLP-1 Care for Women 40+

Semaglutide Injection

Join 100,000+ other patients

For weight gain that
feels different after 40.

See if you qualify

No charge today Takes about 3 minutes

Board-certified physicians
State-licensed pharmacies
Same-day prescriptions
2-day shipping

Compounded semaglutide injection — Cypress Health

2-day shipping · direct-to-door
Cancel anytime on monthly · save more on 6 or 12-month plans
Includes clinician oversight, dose escalation, and side-effect support

Your care

U.S.-LicensedPhysicians

State-LicensedCompounding Pharmacies

HIPAACompliant

Available inAll 50 US states

Pricing

Choose your plan.

Save more with the 6 or 12-month plan.

Why semaglutide

A first step most women tolerate well.

Compounded semaglutide injection for weight loss

The active ingredient — semaglutide — has been studied extensively for weight management. The dose ramp is gentle, the side-effect profile is well understood, and most women find compounded semaglutide tolerable from the start.

For women in midlife, semaglutide is often the first GLP-1 we recommend. If response plateaus or doesn't reach goals, your clinician can talk through whether tirzepatide or a different protocol might fit better.

Whether semaglutide is right for you depends on your medical history, current medications, and goals. Your clinician will determine that. The intake is the first step.

Dosing

A measured start. Adjusted as you go.

Weeks 1–4 · Starting dose

0.25 mg once weekly. The starting dose is intentionally low to let your body adjust; mild GI symptoms are common in the first week or two and typically settle.

Weeks 5+ · Dose escalation

Your clinician adjusts your dose — typically 0.5 mg, 1.0 mg, 1.7 mg, 2.4 mg over time, based on response, tolerance, and goals.

Ongoing · Care, not just refills

Your plan includes ongoing clinician oversight, dose adjustment, side-effect support, and lab review when needed.

Side effects & safety

What to know before you start.

Woman reviewing health information at home

Most common: nausea, decreased appetite, mild diarrhea, constipation, fatigue. Typically dose-related and most pronounced in the first week of each new dose.

Less common but important: pancreatitis, gallbladder issues, low blood sugar (especially if you also take insulin or sulfonylureas). Tell your clinician about all current medications.

Muscle mass during treatment: GLP-1 therapy can be associated with loss of lean mass, particularly in women in midlife. Your clinician will discuss strategies to protect muscle — typically resistance training and adequate dietary protein — as part of your care plan.

Not appropriate if: you have a personal or family history of medullary thyroid carcinoma or MEN2; you're pregnant, planning pregnancy, or breastfeeding; or you have severe GI disease or end-stage organ disease.

Questions

Answers to
common questions.

How is compounded semaglutide prepared?

Compounded by a licensed 503A pharmacy on a per-patient basis.

Compounded semaglutide is prepared by a state-licensed U.S. pharmacy operating under Section 503A of the Federal Food, Drug, and Cosmetic Act. Each preparation is dispensed per-patient based on a licensed clinician's prescription. Compounded preparations are not interchangeable with branded medications and may differ in formulation, strength, and clinical profile. Your clinician will help determine whether compounded semaglutide is appropriate for your specific health profile.

How quickly should I expect to see results?

Most women notice appetite changes within 1–2 weeks; weight changes typically follow within the first month.

Most women notice appetite changes within the first one to two weeks and start to see scale movement within the first month. The largest published trial of injectable semaglutide for weight management — STEP 1 (Wilding et al., NEJM 2021) — showed an average ~14.9% body weight loss over 68 weeks at the 2.4 mg weekly dose. Outcomes from clinical trials of branded products cannot be directly attributed to compounded preparations. Your individual response depends on dose, time, lifestyle, and biology.

When am I charged?

Not until a clinician confirms your eligibility — typically within 24–48 hours.

You're not charged when you submit your assessment. Your card is securely saved while a licensed clinician reviews your case, typically within 24 to 48 hours. If you're approved, you'll receive an email confirmation before any charge is processed. If you're not approved, you're not charged at all.

Will I need to stay on treatment after I reach my goal?

Most people regain weight without a structured maintenance plan. We plan that step with you, not around you.

This is one of the most important conversations you'll have with your clinician. The available evidence — including the STEP 4 withdrawal trial (Rubino et al., JAMA 2021) — shows that most people regain weight when they stop GLP-1 therapy without a structured maintenance plan. Some women step down to a lower maintenance dose; some wean off with continued resistance training and protein-forward eating to preserve lean mass; some choose to continue at full dose. There's no single right answer, and the right path is decided with you.

Can I cancel?

Cancel anytime on monthly.

The 1-month plan can be cancelled at any time. The 6 and 12-month plans are billed upfront for the full term and shipped quarterly — you can choose not to renew at the end of your term.

Is insurance required?

No — transparent flat-rate pricing, no hidden fees.

No. Cypress offers transparent, flat-rate pricing without insurance and no hidden fees. Medication, supplies, and shipping are all included.

Can I use my FSA/HSA?

Yes — itemized receipts provided for self-submission.

Yes. HSA and FSA cards are accepted on any plan. We also provide itemized receipts in case you need to self-submit to your benefits provider.

See if semaglutide is right for you.

The 3-minute medical screener is free. If you're a candidate, your clinician typically follows up within 24 hours.